Buprenorphine, Semi-Quantitative

Test MnemonicBuprenorphine, Semi Quant
CPT Code80307
Also Known AsBup
Specimen TypeUrine
Specimen ContainerPlastic container w/ tightly fitting cap
Alternate Speciman TypeNone
Preferred Volume1.0 mL
Minimum Volume0.5 mL
Specimen CollectionRoutine voided urine collection
Specimen ProcessCollect freshly voided urine in plastic containers
Specimen Transport StorageRefrigerated
Specimen Stability7 days refrigerated (2-8°C); 2 weeks frozen (-20°C or less)
Specimen Rejection• Improperly labeled.
• Incomplete information on the requisition.
• Too old for processing.
• Failure to meet volume criteria.
• Leaking primary or secondary specimen container.
• Wrong collection container for test ordered.
• Gross contamination.
• Improper storage
MethodologyEnzyme Immunoassay
UseFor the qualitative determination of the presence of buprenorphine in human urine at a cut off concentration of 5 ng/mL.
Clinical SignifiganceBuprenorphine is a semi-synthetic opioid analgesic derived from thebaine, a component of opium. Buprenorphine resembles morphine structurally but has both antagonist and agonist properties. Buprenorphine has a longer duration of action than morphine and can be administered sublingually as an analgesic. Subutex, a higher dose buprenorphine formulation is widely used in Europe and the US as a substitute treatment for opiate addiction.
Reference Range< 5 ng/mL is negative
Day RunMon-Fri
Time RunAs Received
Time Reported3 days
Test TypeTox